T1 mapping, ECV and ICV before and after aortic valve replacement

نویسندگان

  • Emmanuelle Vermes
  • Nicolas Cazeneuve
  • Olivier Genee
  • Anne Delhommais
  • Laurent Brunereau
  • Daniel Alison
  • Julien Pucheux
چکیده

Methods A prospective CMR T1 mapping study of 37 patients with severe AS before and six months after aortic valve replacement (AVR) was conducted. CMR at 1.5 T, including T1 mapping using a modified Look-Locker inversion recovery sequence (before and 15 minutes after the administration of 0.2 mmol/kg of Gadoteric acid), was carried out. Global T1 values, ECV, ICV have been measured before and six months after surgery.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prognostic value of dual T1 mapping to predict adverse events in TAVR-patients: extra cellular volume as a possible predictor for peri- and post-TAVR adverse events

Background The benefit of a transcatheter aortic valve replacement (TAVR) can differ in patients and therapy bears severe risks. Dual T1 mapping allows for a comprehensive assessment of myocardial tissue by quantification of extracellular volume (ECV) by measuring T1-relaxation before and after administration of Gadolinium(Gd). High degree aortic stenosis can lead to cardiac damage such as diff...

متن کامل

Adenosine stress native T1 mapping in severe aortic stenosis: evidence for a role of the intravascular compartment on myocardial T1 values

BACKGROUND Myocardial T1 relaxation times have been reported to be markedly abnormal in diverse myocardial pathologies, ascribed to interstitial changes, evaluated by T1 mapping and calculation of extracellular volume (ECV). T1 mapping is sensitive to myocardial water content of both intra- and extracellular in origin, but the effect of intravascular compartment changes on T1 has been largely n...

متن کامل

Assessment of diffuse myocardial fibrosis in aortic valve stenosis: let's get personal.

Owing to continuous advances in both cardiovascular surgery and interventions, there is nowadays a whole range of therapeutic options that can be offered to patients with valvular heart disease. In the case of aortic valve stenosis, patients without major co-morbidities can undergo surgical aortic valve replacement (AVR) at a very low surgery-related risk for major adverse events. On the other ...

متن کامل

Pre- and post-contrast T1 mapping for detection of myocardial fibrosis in severe aortic stenosis before and after aortic valve replacement

Background Severe aortic stenosis (AS) leads to diffuse fibrosis in the myocardium, which could cause poor clinical outcome. Cardiovascular Magnetic Resonance (CMR) with recently T1 mapping is a promising technique to identify diffuse myocardial fibrosis. The Objective of the present study was to assess myocardial fibrosis by CMR using T1 mapping in patients with surgical AS and evaluate the ev...

متن کامل

Myocardial extracellular volume fraction and myocardial fibrosis by cmr in patients with severe aortic stenosis

Background Severe aortic stenosis (AS) induces diffuse interstitial myocardial fibrosis (MF). CMR late gadolinium enhancement (LGE) technique is useful to detect focal MF. The amount of MF is associated with worse long-term prognosis after aortic valve replacement surgery (AVR). Measurements of T1 relaxation times before and after gadolinium administration allow determination of myocardial extr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 17  شماره 

صفحات  -

تاریخ انتشار 2015